Biomarker Analysis Services
Longitudinal Analysis and validation
Biomarker analysis can be implemented at every stage of drug research and development, using a wide range of biological matrices including cell cultures, serum, plasma, urine, tissue extracts, and more. These analyses enable the identification of biomarker patterns associated with disease progression, therapeutic response, as well as metabolic and toxicity profiles.
NEPHRIX Biosolutions offers integrated biomarker services covering discovery, gene expression analysis, microRNA profiling, signaling and metabolite assessment. Beyond conventional technics such as Western blot and ELISA, our services rely on advanced singleplex and multiplex platforms, including qRT-PCR, Meso Scale Discovery (MSD) multi-array technology, Luminex assays, flow cytometry, and cytometric bead-based assays, ensuring robust, sensitive, and translationally relevant data.
| Biomarker Category | Specific Biomarkers | Key Applications |
|---|---|---|
| Renal Function Markers | Serum creatinine, Blood urea nitrogen (BUN), Cystatin C |
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| Markers of Kidney Damage | Albuminuria, Proteinuria, KIM-1, NGAL |
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| Inflammatory Markers | IL-6, TNF-α, MCP-1, IL-1β |
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| Fibrosis Markers | TGF-β, Collagen IV, Fibronectin, α-SMA |
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| Emerging & Novel Biomarkers | Uromodulin, suPAR, FGF-23, Urinary exosomal miRNAs |
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| Custom Biomarker Assays | Client-specified targets (novel proteins, metabolites) |
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