In Vitro Assay Services
Validate new molecules and secure your next go-to in vivo step with our CRO
Using our in vitro models, we assess new leads from your libraries by testing their nephrotoxicity and efficacy (on selected parameters) in a month.
Exploration of the molecular mechanisms or the in vivo validation are based on Go/No-Go decisions.
Characteristics of our innovative solutions :
- Shows >80% of physiological features
- High level of drug effects prediction
- Modulable micro-environment
- Reduction of animal tests failures and costs
Cell types
Podocytes
Mesangial
Tubular cells (proximal, TAL, distal)
Endothelial
Fibroblasts
more ...
Environment
Inflammatory
Hyperglycemic
Fibrotic
Hypoxic
Drug toxicity
more ...
Parameters
Cell death &
membrane leakage
Epithelium integrity
Mitochondrial activity
Gene & Protein expression
Channel & transporter function
more ...