Diabetic Nephropathy – STZ rat and mouse

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Diabetic Nephropathy CRO Services

The Streptozotocin (STZ) Rat Model: A Powerful Tool for Diabetic Nephropathy Preclinical Research and Drug Testing.

Diabetic Nephropathy, a common complication of diabetes, presents significant challenges in treatment and management. Our meticulously designed STZ rat model offers researchers a reliable platform to explore the intricate mechanisms underlying this pathological condition including renal fibrosis, inflammation and glomerular alterations.

Why Choose Our Streptozotocin Rat Model?

  1. Reflects Human Pathophysiology: Our model accurately mimics the progression of diabetic nephropathy seen in humans, providing researchers with a faithful representation of the disease’s complexities.

  2. Versatile and Reliable: Whether you’re exploring disease progression, evaluating novel therapeutic interventions, or screening potential drug candidates, our rat model offers versatility and reliability in experimental outcomes.

  3. Highly Reproducible Results:  Our STZ rat model delivers reproducible results, enabling confident data interpretation and robust scientific conclusions.

  4. Ethical and Compliant: We adhere to the highest ethical standards and regulatory guidelines in animal research, ensuring the welfare and well-being of our animal subjects at every stage.

Partner with us to advance your research goals and accelerate the development of innovative therapies for Diabetic Nephropathy.

Kidney Preclinical research

Usually rats but validated also in mice with multiple low dose injections

From 8 to 12 weeks allowing a longitudinal evaluation of therapeutic compounds

Multiple parametric analyses, including histopathology, biochemistry, and gene expression studies

Study design STZ rat

Design STZ rats

Assay readouts

Kidney Preclinical research