Nephrotoxicity model
Cisplatin induced AKI model, the gold standard of kidney models
The cisplatin-induced acute kidney injury (AKI) model is widely used to study kidney toxicity and evaluate potential treatments. This model closely mimics human drug-induced nephrotoxicity, making it a valuable tool for understanding kidney damage mechanisms and testing new therapies aimed at mitigating acute renal injury.
Why Choose Our Cisplatin induced AKI model?
- Proven Efficacy: Backed by extensive research, our cisplatin-induced AKI model consistently delivers reliable results, enabling researchers to validate proof-of-concept studies in nephrotoxicity.
- Optimized Test Duration: With a concise test duration of only three days, our model streamlines in vivo nephrotoxicity screening, saving time and resources without compromising accuracy.
- Comprehensive Analysis: Gain in-depth insights with our multi-faceted approach, including histopathology, biochemistry, and gene expression studies, maximizing data output from each experimental animal.
Contact us to learn more about how we can support your scientific endeavors with our nephrotoxicity model.
Usually Mouse C57Bl6/J male mice
Suitable for drug screening: 1 to 5 days
Multiple parametric analyses, including histopathology, biochemistry, and gene expression studies
Study design
✓ Blood/Urine chemistry
✓ Gene expression analysis
✓ Histology, Kidney Injury Score
Assay readouts
