Nephrotoxicity model
Cisplatin induced AKI model, the gold standard of kidney models
The cisplatin-induced acute kidney injury (AKI) model is widely used to study kidney toxicity and evaluate potential treatments. This model closely mimics human drug-induced nephrotoxicity, making it a valuable tool for understanding kidney damage mechanisms and testing new therapies aimed at mitigating acute renal injury. Why Choose Our Cisplatin induced AKI model?- Proven Efficacy: Backed by extensive research, our cisplatin-induced AKI model consistently delivers reliable results, enabling researchers to validate proof-of-concept studies in nephrotoxicity.
- Optimized Test Duration: With a concise test duration of only three days, our model streamlines in vivo nephrotoxicity screening, saving time and resources without compromising accuracy.
- Comprehensive Analysis: Gain in-depth insights with our multi-faceted approach, including histopathology, biochemistry, and gene expression studies, maximizing data output from each experimental animal.
Usually Mouse C57Bl6/J male mice
Suitable for drug screening: 1 to 5 days
Multiple parametric analyses, including histopathology, biochemistry, and gene expression studies
Study design
✓ Blood/Urine chemistry
✓ Gene expression analysis
✓ Histology, Kidney Injury Score
Assay readouts
