STZ Model – The Streptozotocin-Induced Rat & Mouse Model

A powerful tool for Diabetic Nephropathy preclinical research and drug testing
 

Diabetic Nephropathy, a common complication of diabetes, presents significant challenges in treatment and management. Our meticulously designed STZ rat & mouse model offers researchers a reliable platform to explore the intricate mechanisms underlying this pathological condition including renal fibrosis, inflammation and glomerular alterations.

Why Choose Our Streptozotocin (STZ) Rat & Mouse Model?

  • Reflects Human Pathophysiology: Our model accurately mimics the progression of diabetic nephropathy seen in humans, providing researchers with a faithful representation of the disease’s complexities.
  • Versatile and Reliable: Whether you’re exploring disease progression, evaluating novel therapeutic interventions, or screening potential drug candidates, our rat model offers versatility and reliability in experimental outcomes.
  • Highly Reproducible Results:  Our STZ rat model delivers reproducible results, enabling confident data interpretation and robust scientific conclusions.
  • Ethical and Compliant: We adhere to the highest ethical standards and regulatory guidelines in animal research, ensuring the welfare and well-being of our animal subjects at every stage.

Partner with us to advance your research goals and accelerate the development of innovative therapies with our validated STZ Rat & Mouse Model

Kidney Preclinical research

Usually rats but validated also in mice with multiple low dose injections

From 8 to 12 weeks allowing a longitudinal evaluation of therapeutic compounds

Multiple parametric analyses, including histopathology, biochemistry, and gene expression studies

Study design STZ rat model

Kidney Preclinical research

Assay readouts

Kidney Preclinical research
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