Validate new molecules and secure your next go-to-in vivo step

Using our models, we assess new leads from your libraries by testing their toxicity and efficacy (on selected parameters) in a month.
Exploration of the molecular mechanisms or the in vivo validation are based on Go/No-Go decisions.

Characteristics of our innovative solutions :

  • Shows >80% of physiological features
  • High level of drug effects prediction
  • Modulable micro-environment
  • Reduction of animal tests failures and costs

Cell types

Podocytes
Mesangial
Tubular cells (proximal, TAL, distal)
Endothelial
Fibroblasts
..

Environment

Inflammatory
Hyperglycemic
Fibrotic
Hypoxic
Drug toxicity
...

Parameters

Cell death & membrane leakage
Epithelium integrity
Mitochondrial activity
Gene & Protein expression
Channel & transporter function
...

Co-cultures systems to demonstrate the preclinical proof-of-concept of your drug.