Validate new molecules and secure your next go-to-in vivo step
Using our models, we assess new leads from your libraries by testing their toxicity and efficacy (on selected parameters) in a month.
Exploration of the molecular mechanisms or the in vivo validation are based on Go/No-Go decisions.
Characteristics of our innovative solutions :
- Shows >80% of physiological features
- High level of drug effects prediction
- Modulable micro-environment
- Reduction of animal tests failures and costs
Cell types
Podocytes
Mesangial
Tubular cells (proximal, TAL, distal)
Endothelial
Fibroblasts
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Environment
Inflammatory
Hyperglycemic
Fibrotic
Hypoxic
Drug toxicity
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Parameters
Cell death &
membrane leakage
Epithelium integrity
Mitochondrial activity
Gene & Protein expression
Channel & transporter function
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