Cisplatin induced AKI model
Discover the Gold Standard in nephrotoxicity and explore potential therapeutic interventions.
The cisplatin-induced acute kidney injury (AKI) mouse model is widely used to study nephrotoxicity and evaluate potential treatments. This model closely mimics human drug-induced nephrotoxicity, making it a valuable tool for understanding kidney damage mechanisms and testing new therapies aimed at mitigating acute renal injury.
Why Choose Our Cisplatin induced AKI model?
- Proven Efficacy: Backed by extensive research, our cisplatin-induced AKI model consistently delivers reliable results, enabling researchers to validate proof-of-concept studies in nephrotoxicity.
- Optimized Test Duration: Wth a concise test duration of only two days, our model streamlines in vivo nephrotoxicity screening, saving time and resources without compromising accuracy.
- Comprehensive Analysis: Eain in-depth insights with our multi-faceted approach, including histopathology, biochemistry, and gene expression studies, maximizing data output from each experimental subject.
Additionally to our in vivo model, we also offer the possibility to screen your compounds in our validated in vitro cisplatin assay.
Usually Mouse C57Bl6/J male mice
Suitable for drug screening: 1 to 5 days
Multiple parametric analyses, including histopathology, biochemistry, and gene expression studies
Study design
✓ Blood/Urine chemistry
✓ Gene expression analysis
✓ Histology, Kidney Injury Score
Assay readouts
